熊本大学大学院生命科学研究部 

2018年

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【著書】

1. 魏 范研、富澤一仁.RNAイオウ編集の分子機構と代謝疾患、実験医学増刊 レドックス疾患学(赤池孝章、本橋ほづみ、内田浩二、末松 誠編)、Pp114-120、羊土社、東京、2018.

【総説】

1. Wei, F.-Y., and Tomizawa, K. tRNA modifications and type 2 diabetes. Diabetes Obes. Metab. Supple 2, 20-27, 2018.

【原著論文】

1. Fakruddin, M., Wei, F.-Y., Suzuki, T., Asano, K., Kaieda, T., Omori, A., Fujimura, A., Kaitsuka, T., Miyata, K., Araki, K., Oike, Y., Scorrano, L., Suzuki, T., and Tomizawa, K. Defective mitochondrial tRNA taurine-modification activates global proteostress and leads to mitochondrial disease. Cell Rep. 22, 482-496, 2018.

2. Asano, K., Suzuki, T., Saito, A., Wei, F.-Y., Ikeuchi, Y., Numata, T., Tanaka, R., Yamane, Y., Yamamoto, T., Goto, T., Kishita, Y., Murayama, K., Ohtake, A., Okazaki, Y., Tomizawa, K., Sakaguchi, Y. and Suzuki, T. Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease. Nucl. Acids Res. 46, 1565-1583, 2018.

3. Futakuchi, A., Inoue, T., Wei, F.-Y., Inoue-Mochita, M., Fujimoto, T., Tomizawa, K., and Tanihara, H. YAP/TAZ are essential for TGF-β2-mediated conjunctival fibrosis. Invest. Ophthalmol. Vis. Sci. 59, 3069-3078, 2018.

4. Kaitsuka, T., Kiyonari, H., Shiraishi, A., Tomizawa, K., and Matsushita, M. Deletion of long isoform of eukaryotic elongation factor 1Bδ leads to audiogenic seizures and aversive stimulus-induced long-lasting activity suppression in mice. Front. Mol. Neurosci. 11, 358, 2018.

5. Latt, H.M., Matsushita, H., Morino, M., Koga, Y., Michiue, H., Nishiki, T., Tomizawa, K., and Matsui, H. Oxytocin inhibits corticosterone-induced apoptosis in primary hippocampal neurons. Neuroscience, 379, 383-389, 2018.

6. Sakakida, K., Wei, F.-Y., Senokuchi, T., Shimoda, S., Kakuma, T., Araki, E. and Tomizawa, K. Study design of a phase II clinical trial to assess the efficacy and safety of eperisone in Japanese type 2 diabetes patients with risk and non-risk alleles of CDKAL1. Acta Medica Okayama 72, 423-426, 2018.

7. Islam, MS, Wei, F.-Y., Ohta, K., Shigematsu, N., Fukuda, T., Tomizawa, K., and Yamagata, K. Sirtuin 7 is involved in the consolidation of fear memory in mice. Biochem. Biophys. Res. Commun. 495, 261-266, 2018.

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