熊本大学大学院生命科学研究部 

2017年

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【著書】

・富澤一仁.CPPペプチドを用いたiPS細胞作製分化誘導技術.医療をささえるペプチド科学-再生医療・DDS・診断への応用(平野義明編)Pp95-100、シーエムシー出版、東京、2017.

【総説】

・富澤一仁.硫黄分子によるtRNAのチオメチル化修飾とその生理的意義.硫酸と工業 70: 131-138, 2017.

・富澤一仁.tRNA修飾と環境応答.最新医学 72: 693-702, 2017.

【原著論文】

・Fakruddin, M., Wei, F.-Y., Emura, S., Matsuda, S., Yasukawa, T., Kang, D., and Tomizawa, K. Cdk5rap1-mediated 2-methylthio-N6-isopentenyladenosine modification does not exist in nuclear-derived RNA species. Nucl. Acid Res. 45, 11954-11961, 2017.

・Takahashi, N., Wei, F.-Y., Watanabe, S., Hirayama, M., Ohuchi, Y., Fujimura, A., Kaitsuka, T., Sawa, T., Nakayama, H., Akaike, T. and Tomizawa, K. Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion. Nucl. Acid Res. 45, 435-445, 2017.

・Akaike, T, Ida, T., Wei, F.-Y., Nishida, M., Kumagai, Y., Morshedul Alam, M., Ihara, H., Mizanur Rahaman, M., Matsunaga, T., Kasamatsu, S., Nishimura, A., Morita, M., Tomizawa, K., Nishimura, A., Watanabe, S., Inaba, K., Shima, H., Tanuma, N., Jung, M., Fujii, S., Watanabe, Y., Munuraya, M., Nagy, P., Feelish, M., Fukuto, H.M., Motohashi, H. Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics. Nat Commun. 8, 1177, 2017.

・Saito, M., Otsu, W., Hsu, K.-S., Chuang, J.-Z., Yanagisawa, T., Vincent Shieh, V., Kaitsuka, T., Wei, F.-Y., Tomizawa, K., and Sung, C.-H. Tctex-1, Cdc42, and actin regulate clathrin-dependent endocytosis to control primary ciliary resorption. EMBO Rep. 18, 1460-1472, 2017.

・Kaitsuka, T., Kobayashi, K., Otsuka, W., Kubo, T., Hakim, F., Wei, F.Y., Shiraki, N., Kume, S., and Tomizawa, K. Erythropoietin facilitates definitive endodermal differentiation of mouse embryonic stem cells via activation of ERK signaling. Am. J. Physiol.-Cell Physiol. 312, C573-C582, 2017.

・Ono, K., Jung M., Zhang, T., Tsutsuki, H., Sezaki, S., Ihara, H., Wei, F.-Y., Tomizawa, K., Akaike, T., and Sawa T. Synthesis of L-cysteine derivatives containing stable sulfur isotopes and application of this synthesis to reactive sulfur metabolome. Free Radic. Biol. Med. 106, 69-79, 2017.

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