熊本大学大学院生命科学研究部 

2012年

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【総説】
・Wei, F.Y., and Tomizawa, K. Development of type 2 diabetes caused by a deficiency of a tRNAlys modification. Islets 4, 71-73, 2012.
・Matsuzaki, M., Matsushita, H., Tomizawa, K., and Matsui, H. Oxytocin: A therapeutic target for mental disorders. J. Physiol. Sci.62,441-444,2012.※selected to the most downloaded paper in 2012.
・富澤一仁.日本人種型2型糖尿病関連遺伝子、Cdkal1の生理機能。医学のあゆみ 240: 318-319, 2012.

【原著論文】
・Ueda, Y., Wei, F.-Y., Hide, T., Michiue, H., Takayama K., Kaitsuka, T., Nakamura, H., Makino, K., Kuratsu, J., Futaki, S., and Tomizawa, K.  Induction of autophagic cell death of glioma-initiating cells by cell-penetrating D-isomer peptides consisting of Pas and the p53 C-terminus.Biomaterials 33, 9061-9069, 2012.
・Candan, G., Michiue, H., Ishikawa, S., Fujimura, A., Hayashi, K., Uneda, A., Mori, A., Ohmori, I., Nishiki, T., Matsui, H., and Tomizawa, K. Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery. Biomaterials 33, 6468-6475, 2012.
・ Sato, Y., Hatta, M., Karim, M.F., Sawa, T., Wei, F.Y., Sato, S., Magnuson, M.A., Gonzalez, F.J., Tomizawa, K., Akaike, T., Yoshizawa, T., and Yamagata, K. Anks4b, a novel target of HNF4α interacts with GRP78 and regulates endoplasmic reticulum stress-induced apoptosisin pancreatic β-cells. J. Biol. Chem. 287, 23236-23245, 2012.
・ Hitsuda, T., Michiue, H., Kitamatsu, M., Wang, F. Fujimura, A., Yamamoto, T., Han, X.-J., Tazawa, H., Uneda, A., Ohmori, I., Nishiki, T., Tomizawa, K., and Matsui, H. A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors in to cell nuclei. Biomaterials 33, 4665-4672, 2012.
・ Okimoto, N., Oliver, J.B., Slattery, D.A., Pflaum K., Matsushita, H., Wei, F.-Y., Ohmori, M., Nishiki, T., Ohmori, I., Hiramatsu, Y., Matsui, H., Neumann, I.D., and Tomizawa, K. RGS2 mediates the anxilolytic effect of oxytocin. Brain Res. 1453, 26-33, 2012.
・ Matsushita, H., Matsuzaki, M., Han, X.-J., Nishiki, T., Ohmori, I., Michiue, H., Matsui, H., and Tomizawa, K. Antidepressant effect of sildenafil through oxytocin-dependent CREB phosphorylation. Neuroscience 200, 13-18, 2012.
・ Masumoto, T., Suzuki, K., Ohmori, I., Michiue, H., Tomizawa, K., Fujimura, A., Nishiki, T., and Matsui H. Ca2+-independent syntaxin binding to the C2B effector region of synaptotagmin. Mol. Cell. Neurosci. 49, 1-8, 2012.

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