熊本大学大学院生命科学研究部 

2007年

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【著書】
・ 富澤一仁.Cdk5によるインスリン分泌制御.分子糖尿病学の進歩ー基礎から臨床までー2007(矢崎義雄監修):10-13, 2007(金原出版).

【総説】
・ Wei, F.-Y., and Tomizawa, K. Cyclin-dependent kinase 5 (Cdk5); A potential therapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus. Mini Rev. Med. Chem. 7: 1070-1074, 2007.
・ Wu, H.-Y., Tomizawa, K., and Matsui, H. Calpain-calcineurin signal in the pathogenesis of calcium-dependent disorder. Acta Medica Okayama 61: 123-137, 2007
・ 富澤一仁、松井秀樹.蛋白質セラピー法.再生医療 6: 51-57, 2007.

【原著論文】
・ Wu, Y., Liang, S., Oda, Y., Ohmori, I., Nishiki, T., Takei, K., Matsui, H., and Tomizawa, K. Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation. EMBO J. 26, 2981-2990, 2007.
・ Kitani, K., Oguma, S., Nishiki TI, Ohmori, I., Galons, H., Matsui, H., Meijer L., and Tomizawa, K. A Cdk5 inhibitor enhances induction of insulin secretion by exendin-4 both in vitro and in vivo. J. Physiol. Sci. 57, 235-239, 2007.
・ Yamada, H., Ohashi E., Kusumi N., Li, S.-A., Yoshida Y., Watanabe, M., Tomizawa, K., Kashiwakura, Y., Kumon, H., Matsui H., and Takei K. Amphiphysin I is important for actin polymerization duirng phagocytosis. Mol. Cell Biol. 18, 4669-4680, 2007.
・ Tsutsui, Y., Tomizawa, K., Nagita, M., Nishiki, T., Ohmori I., Seno M., and Matsui, H. Development of bionanocapsules targeting brain tumors. J. Control. Release 122, 159-164, 2007.
・ Liang, S., Wei, F.-Y., Wu, Y.-M., Tanabe K., Abe, T., Oda, Y., Yoshida, Y., Yamada, H., Matsui, H., Tomizawa, K., and Takei, K. Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis. J. Neurochem. 102, 1466-1476, 2007.
・ Ogawa, N., Ono, S., Ichikawa, T., Arimitsu, S., Onoda, K., Tokunaga, K., Sugiu, K., Tomizawa, K., Matsui, H., and Date, I. Novel protein transduction method by using 11R. An effective new drug delivery system fro the treatment of cerebrovascular diseases. Stroke 38, 1354-1361, 2007
・ Wu, Y., Tada, M., Takahata, K., Tomizawa, K., and Matsui, H. Inhibitory effect of polyunsaturated fatty acids on apoptosis induced by etoposide, okadaic acid and AraC in neuro2a cells. Acta Medica Okayama 61, 147-152, 2007.
・ Fujisawa, T., Moriwaki, A., Matsushita, M., Tomizawa, K., and Matsui, H. Colocalization of oxytocin and phosphorylated form of elongation factor 2 in the rat hypothalamus. Acta Medica Okayama 61, 161-166, 2007.
・ Tanaka F., Chosrowjan H., Taniguchi S., Mataga N., Sato K., Nishina Y., & Shiga K. Donor–acceptor distance-dependence of photoinduced electron-transfer rate in flavoproteins. Journal of Physical Chemistry B. 111, 5694–5699, 2007.
・ Nishina Y., Sato K., Setoyama C., Tamaoki H., Miura R., & Shiga K. Intramolecular and intermolecular perturbation on electronic state of FAD free in solution and bound to flavoproteins: FTIR spectroscopic study by using the C=O stretching vibrations as probes. Journal of Biochemistry. 142, 265–272, 2007

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